Synthesis and antimicrobial screening of pyrazolo-3-aryl quinazolin-4(3h)ones
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چکیده
منابع مشابه
Synthesis and Antimicrobial Screening of Pyrazolo-3-Aryl Quinazolin-4(3H)ones
2-thio-3-aryl quinazolin-4(3H)one (1) was synthesized by reacting anthranilic acid with thiocarbamate salts of substituted aniline and carbon disulphide, which on reflux with excess of hydrazine hydrate to form 2-hydrazino quinazolin-4(3H)one derivatives (2). The reaction of (2) with variously substituted aryl aldehydes gave the corresponding hydrazones (3). Further, the cyclization of compound...
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an efficient synthesis of some novel coumarin derivatives via 1, 4- michael addition of indole to coumarin chalcones catalyzed by cellulose sulphonic acid (csa) under solvent free conditions is described. the corresponding michael addition products were obtained in good to excellent yield. the synthesized compounds were screened for their antibacterial activity against e. coli, s. aureus and an...
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ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2010
ISSN: 0250-474X
DOI: 10.4103/0250-474x.73934